April 16, 2024

Gene Silencing Market Size to Worth USD 8.48 Billion by 2033

The gene silencing market size is poised to grow by USD 8.48 billion by 2033 from USD 4.02 billion in 2023, exhibiting a CAGR of 7.80% during the forecast period 2024 to 2033.

Key Points

  • North America held the largest share of 44% in the market in 2023.
  • On the other hand, Asia Pacific is observed to witness the fastest CAGR of 9.8% during the forecast period.
  • By type, the transcriptional segment held the largest share of 53% in 2023 in the gene silencing market.
  • On the other hand, the post-transcriptional segment is expected to witness a substantial growing CAGR of 8.8% during the forecasted period.
  • By application, the neurological diseases treatment segment dominated the market with a 41% market share in 2023.

Gene Silencing Market Size 2024 to 2033

The gene silencing market is witnessing significant growth driven by advancements in molecular biology, increasing research activities in genetic diseases, and the growing demand for personalized medicine. Gene silencing, a process that regulates gene expression by inhibiting the transcription or translation of specific genes, has emerged as a promising therapeutic approach for various diseases, including cancer, genetic disorders, and infectious diseases. This market encompasses a range of technologies, including RNA interference (RNAi), antisense oligonucleotides, and CRISPR/Cas9, which offer targeted and precise mechanisms for manipulating gene expression.

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Growth Factors

Several factors contribute to the growth of the gene silencing market. The increasing prevalence of chronic diseases such as cancer, cardiovascular disorders, and neurological conditions is driving the demand for innovative therapies. Additionally, advancements in biotechnology and genetic engineering have facilitated the development of more efficient and specific gene silencing techniques. Moreover, the expanding applications of gene silencing in agriculture and biotechnology sectors are opening new avenues for market growth. Furthermore, rising investments in research and development activities by pharmaceutical and biotechnology companies are fueling the expansion of the gene silencing market.

Gene Silencing Market Scope

Report Coverage Details
Growth Rate from 2024 to 2033 CAGR of 7.80%
Global Market Size in 2023 USD 4.02 Billion
Global Market Size by 2033 USD 8.48 Billion
U.S. Market Size in 2023 USD 1.24 Billion
U.S. Market Size by 2033 USD 2.66 Billion
Base Year 2023
Forecast Period 2024 to 2033
Segments Covered By Type and By Application
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa

Read More: Fiber Optic Sensing System Market Size to Worth USD 7.23 Bn by 2033

Opportunities

The gene silencing market presents numerous opportunities for further expansion and innovation. One significant opportunity lies in the development of targeted delivery systems to enhance the efficacy and safety of gene-silencing therapeutics. Nanotechnology-based delivery systems, lipid nanoparticles, and viral vectors are among the promising approaches being explored to achieve efficient delivery of gene-silencing agents to target cells or tissues. Additionally, the increasing adoption of personalized medicine and the growing understanding of genetic variations among individuals are driving the demand for customized gene therapies, creating opportunities for market players to develop tailored solutions for specific patient populations.

Challenges

Despite its promising potential, the gene silencing market faces several challenges that need to be addressed for sustained growth. One of the primary challenges is the off-target effects associated with gene silencing therapies, which can lead to unintended consequences and adverse reactions. Ensuring the specificity and safety of gene-silencing agents remains a significant concern for researchers and developers. Moreover, the high cost of gene therapy and the complexity of regulatory approval processes pose challenges for market penetration and commercialization. Additionally, ethical and societal considerations surrounding genetic manipulation and gene editing technologies, such as CRISPR/Cas9, raise questions about the responsible use of these techniques and may influence public acceptance and regulatory decisions. Addressing these challenges will be crucial for unlocking the full potential of the gene silencing market and realizing its benefits in healthcare and other fields.

Gene Silencing Market Companies

  • Alnylam Pharmaceuticals (USA)
  • Arrowhead Pharmaceuticals (USA)
  • Dicerna Pharmaceuticals (USA)
  • Ionis Pharmaceuticals (USA)
  • Quark Pharmaceuticals (Israel)
  • Benitec Biopharma (Australia)
  • Sirnaomics (USA)
  • Silence Therapeutics (United Kingdom)
  • OliX Pharmaceuticals (South Korea)
  • Arcturus Therapeutics (USA)
  • Sylentis (Spain)
  • Exicure (USA)
  • miRagen Therapeutics (USA)
  • Regulus Therapeutics (USA)
  • Rxi Pharmaceuticals (USA)

Data Sources and Methodology

To gather comprehensive insights on the Global Gene silencing Market, we relied on a range of data sources and followed a well-defined methodology. Our approach involved interactions with industry experts and key stakeholders across the market’s value chain, including management organizations, processing organizations, and analytics service providers.

We followed a rigorous data analysis process to ensure the quality and credibility of our research. The gathered information was carefully evaluated, and relevant quantitative data was subjected to statistical analysis. By employing robust analytical techniques, we were able to derive meaningful insights and present a comprehensive overview of the Global Gene silencing Market.

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  • The research report has been meticulously crafted to provide comprehensive knowledge on essential marketing strategies and a holistic understanding of crucial marketing plans spanning the forecasted period from 2023 to 2032.

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  • Comprehensive Coverage: The report extensively encompasses a detailed explanation of highly effective analytical marketing methods applicable to companies across all industry sectors.
  • Decision-Making Enhancement: It outlines a concise overview of the decision-making process while highlighting key techniques to enhance it, ensuring favorable business outcomes in the future.
  • Articulated R&D Approach: The report presents a well-defined approach to conducting research and development (R&D) activities, enabling accurate data acquisition on current and future marketing conditions.

Market Segmentation:

By Type

  • Transcriptional
  • Post-transcriptional
  • Meiotic

By Application

  • Cancer Treatment
  • Neurological Diseases Treatment
  • Scar Treatment
  • Other

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Reasons to Consider Purchasing the Report:

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  • Gain a thorough understanding of the overall market landscape and be prepared to overcome challenges while ensuring robust growth.
  • Benefit from in-depth research and analysis of the latest trends shaping the global Gene silencing market.
  • Obtain detailed insights into evolving market trends, current and future technologies, and strategic approaches employed by key players in the global Gene silencing market.
  • Receive valuable recommendations and guidance for both new entrants and established players seeking further market expansion.
  • Discover not only the cutting-edge technological advancements in the global Gene silencing market but also the strategic plans of industry leaders.

Table of Content

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology (Premium Insights)

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Gene Silencing Market 

5.1. COVID-19 Landscape: Gene Silencing Industry Impact

5.2. COVID 19 – Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

Chapter 6. Market Dynamics Analysis and Trends

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Gene Silencing Market, By Type

8.1. Gene Silencing Market, by Type, 2024-2033

8.1.1. Transcriptional

8.1.1.1. Market Revenue and Forecast (2021-2033)

8.1.2. Post-transcriptional

8.1.2.1. Market Revenue and Forecast (2021-2033)

8.1.3. Meiotic

8.1.3.1. Market Revenue and Forecast (2021-2033)

Chapter 9. Global Gene Silencing Market, By Application

9.1. Gene Silencing Market, by Application, 2024-2033

9.1.1. Cancer Treatment

9.1.1.1. Market Revenue and Forecast (2021-2033)

9.1.2. Neurological Diseases Treatment

9.1.2.1. Market Revenue and Forecast (2021-2033)

9.1.3. Scar Treatment

9.1.3.1. Market Revenue and Forecast (2021-2033)

9.1.4. Other

9.1.4.1. Market Revenue and Forecast (2021-2033)

Chapter 10. Global Gene Silencing Market, Regional Estimates and Trend Forecast

10.1. North America

10.1.1. Market Revenue and Forecast, by Type (2021-2033)

10.1.2. Market Revenue and Forecast, by Application (2021-2033)

10.1.3. U.S.

10.1.3.1. Market Revenue and Forecast, by Type (2021-2033)

10.1.3.2. Market Revenue and Forecast, by Application (2021-2033)

10.1.4. Rest of North America

10.1.4.1. Market Revenue and Forecast, by Type (2021-2033)

10.1.4.2. Market Revenue and Forecast, by Application (2021-2033)

10.2. Europe

10.2.1. Market Revenue and Forecast, by Type (2021-2033)

10.2.2. Market Revenue and Forecast, by Application (2021-2033)

10.2.3. UK

10.2.3.1. Market Revenue and Forecast, by Type (2021-2033)

10.2.3.2. Market Revenue and Forecast, by Application (2021-2033)

10.2.4. Germany

10.2.4.1. Market Revenue and Forecast, by Type (2021-2033)

10.2.4.2. Market Revenue and Forecast, by Application (2021-2033)

10.2.5. France

10.2.5.1. Market Revenue and Forecast, by Type (2021-2033)

10.2.5.2. Market Revenue and Forecast, by Application (2021-2033)

10.2.6. Rest of Europe

10.2.6.1. Market Revenue and Forecast, by Type (2021-2033)

10.2.6.2. Market Revenue and Forecast, by Application (2021-2033)

10.3. APAC

10.3.1. Market Revenue and Forecast, by Type (2021-2033)

10.3.2. Market Revenue and Forecast, by Application (2021-2033)

10.3.3. India

10.3.3.1. Market Revenue and Forecast, by Type (2021-2033)

10.3.3.2. Market Revenue and Forecast, by Application (2021-2033)

10.3.4. China

10.3.4.1. Market Revenue and Forecast, by Type (2021-2033)

10.3.4.2. Market Revenue and Forecast, by Application (2021-2033)

10.3.5. Japan

10.3.5.1. Market Revenue and Forecast, by Type (2021-2033)

10.3.5.2. Market Revenue and Forecast, by Application (2021-2033)

10.3.6. Rest of APAC

10.3.6.1. Market Revenue and Forecast, by Type (2021-2033)

10.3.6.2. Market Revenue and Forecast, by Application (2021-2033)

10.4. MEA

10.4.1. Market Revenue and Forecast, by Type (2021-2033)

10.4.2. Market Revenue and Forecast, by Application (2021-2033)

10.4.3. GCC

10.4.3.1. Market Revenue and Forecast, by Type (2021-2033)

10.4.3.2. Market Revenue and Forecast, by Application (2021-2033)

10.4.4. North Africa

10.4.4.1. Market Revenue and Forecast, by Type (2021-2033)

10.4.4.2. Market Revenue and Forecast, by Application (2021-2033)

10.4.5. South Africa

10.4.5.1. Market Revenue and Forecast, by Type (2021-2033)

10.4.5.2. Market Revenue and Forecast, by Application (2021-2033)

10.4.6. Rest of MEA

10.4.6.1. Market Revenue and Forecast, by Type (2021-2033)

10.4.6.2. Market Revenue and Forecast, by Application (2021-2033)

10.5. Latin America

10.5.1. Market Revenue and Forecast, by Type (2021-2033)

10.5.2. Market Revenue and Forecast, by Application (2021-2033)

10.5.3. Brazil

10.5.3.1. Market Revenue and Forecast, by Type (2021-2033)

10.5.3.2. Market Revenue and Forecast, by Application (2021-2033)

10.5.4. Rest of LATAM

10.5.4.1. Market Revenue and Forecast, by Type (2021-2033)

10.5.4.2. Market Revenue and Forecast, by Application (2021-2033)

Chapter 11. Company Profiles

11.1. Alnylam Pharmaceuticals (USA)

11.1.1. Company Overview

11.1.2. Product Offerings

11.1.3. Financial Performance

11.1.4. Recent Initiatives

11.2. Arrowhead Pharmaceuticals (USA)

11.2.1. Company Overview

11.2.2. Product Offerings

11.2.3. Financial Performance

11.2.4. Recent Initiatives

11.3. Dicerna Pharmaceuticals (USA)

11.3.1. Company Overview

11.3.2. Product Offerings

11.3.3. Financial Performance

11.3.4. Recent Initiatives

11.4. Ionis Pharmaceuticals (USA)

11.4.1. Company Overview

11.4.2. Product Offerings

11.4.3. Financial Performance

11.4.4. Recent Initiatives

11.5. Quark Pharmaceuticals (Israel)

11.5.1. Company Overview

11.5.2. Product Offerings

11.5.3. Financial Performance

11.5.4. Recent Initiatives

11.6. Benitec Biopharma (Australia)

11.6.1. Company Overview

11.6.2. Product Offerings

11.6.3. Financial Performance

11.6.4. Recent Initiatives

11.7. Sirnaomics (USA)

11.7.1. Company Overview

11.7.2. Product Offerings

11.7.3. Financial Performance

11.7.4. Recent Initiatives

11.8. Silence Therapeutics (United Kingdom)

11.8.1. Company Overview

11.8.2. Product Offerings

11.8.3. Financial Performance

11.8.4. Recent Initiatives

11.9. OliX Pharmaceuticals (South Korea)

11.9.1. Company Overview

11.9.2. Product Offerings

11.9.3. Financial Performance

11.9.4. Recent Initiatives

11.10. Arcturus Therapeutics (USA)

11.10.1. Company Overview

11.10.2. Product Offerings

11.10.3. Financial Performance

11.10.4. Recent Initiatives

Chapter 12. Research Methodology

12.1. Primary Research

12.2. Secondary Research

12.3. Assumptions

Chapter 13. Appendix

13.1. About Us

13.2. Glossary of Terms

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